Transactions of the Twenty-Second Annual Meeting of the Society for Maternal-Fetal MedicineIsolated choroid plexus cyst in low-risk women less than 35 years old☆
Section snippets
Material and methods
A MEDLINE search of the databases of the National Library of Medicine was conducted with the use of the term choroid plexus cyst. Approximately 270 articles have been published on this topic, and approximately 100 of them are on prenatal diagnosis of choroid plexus cysts. We performed a meta-analysis only of articles that met four inclusion criteria. The first criterion was that the study be a prospective trial that had been published in the English language from 1990 through 2000. This time
Results
Thirteen prospective trials were published from 1990 through 2000.11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23 Eight of these trials met our inclusion criteria. Table I details included and excluded trials and gives the incidence of trisomy 18 cases in the screened population during the time period.Included trials* Excluded trials† Ghidini et al10 (2000) Gupta et al18 (1995)‡ Brown et al11 (1999) Kupferminc et al19
Comment
Prenatal diagnosis was provided historically to specific high-risk groups for known high-risk problems. The goal of this focus was to have a positive impact on pregnancies that are at a higher risk for complications without potentially increasing the risk to all pregnancies from the testing. The widespread availability of ultrasonography to both high- and low-risk women and the introduction of maternal serum analyte screening in low-risk women has enabled the detection of chromosomal
References (25)
- et al.
The clinical significance of prenatally diagnosed choroid plexus cyst
Am J Obstet Gynecol
(1989) - et al.
Isolated fetal choroid plexus cysts: role of ultrasonography in establishment of the risk of trisomy 18
Am J Obstet Gynecol
(2000) - et al.
Clinical significance of fetal choroid plexus cysts
Lancet
(1995) - et al.
Isolated choroid plexus cyst(s): an indication for amniocentesis
Am J Obstet Gynecol
(1994) - et al.
Fetal choroid plexus cysts in the second trimester of pregnancy: a cause for concern
Am J Obstet Gynecol
(1991) - et al.
The prenatal diagnosis of transient cysts of the fetal choroid plexus
Prenat Diagn
(1984) - et al.
Rapid karyotyping in non-lethal fetal malformations
Lancet
(1986) - et al.
A prospective study of the incidence and significance of fetal choroid plexus cysts
Prenat Diagn
(1989) - et al.
Choroid plexus cysts in fetuses with trisomy 18
Obstet Gynecol
(1989) - et al.
Fetal choroid plexus cysts: beware the smaller cyst
Radiology
(1992)
Choroid plexus cysts in the fetus: a benign anatomic variant or pathologic entity? Report of 41 cases and review of the literature
Obstet Gynecol
Isolated choroid plexus cysts in the second-trimester fetus: is amniocentesis really indicated?
Radiology
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