Serum Thyroxine and Triiodothyronine Concentrations in Rats Receiving Lithium Carbonate

D. Dhawan; R. Sharma; R. R. Sharma; R. J. Dash

doi:10.1055/s-2007-1013465

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Horm Metab Res 1985; 17(2): 109-110
DOI: 10.1055/s-2007-1013465

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Serum Thyroxine and Triiodothyronine Concentrations in Rats Receiving Lithium Carbonate

D. Dhawan, R. Sharma, R. R. Sharma, R. J. Dash¹

Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
¹Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

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Publication History

1984

1984

Publication Date:
14 March 2008 (online)

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Summary

Circulating thyroxine (T₄) and triiodothyronine (T3) concentrations in rats were determined after various periods of lithium administration in diet. No significant change in serum T₄ and T₃ levels was observed after ten days of lithium treatment. However, lithium treatment for one month, two months and four months showed a significant decrease in serum T₄ and T₃ levels indicating the adverse effect of chronic lithium intake.

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