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Planta Med 2003; 69(4): 316-320
DOI: 10.1055/s-2003-38877
Original Paper
Pharmacology
© Georg Thieme Verlag Stuttgart · New York

Antifungal and Antioxidant Compounds from the Root Bark of Fagara zanthoxyloides

Fatima Chaaib1 , Emerson F. Queiroz1 , Karine Ndjoko1 , Drissa Diallo2 , Kurt Hostettmann1
  • 1Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Lausanne, Switzerland
  • 2Département de Médecine Traditionnelle, INSRP, Bamako, Mali
Further Information

Publication History

Received: July 28, 2002

Accepted: December 7, 2002

Publication Date:
23 April 2003 (online)

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Abstract

Phytochemical investigation of the CH2Cl2 extract of Fagara zanthoxyloides Lam. (Rutaceae) led to the isolation of eleven compounds. One phenylethanoid derivative is a new natural product. The isolation of the antifungal and the antioxidant compounds was monitored by direct TLC bioautographic assays. The structures of the isolated compounds were elucidated by classical spectroscopic methods including UV, NMR, MS and HR-MS.

Key words

Fagara zanthoxyloides - Rutaceae - phenylethanoid derivative - Cladosporium cucumerinum - Candida albicans - Bacillus subtilis - free radical scavengers

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Prof. Kurt Hostettmann

Institute of Pharmacognosy and Phytochemistry

1015 Lausanne

Switzerland

Phone: +41-21-6924561

Fax: +41-21-6924565

Email: kurt.hostettmann@ipp.unil.ch

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