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DOI: 10.1055/s-0034-1382457
Studies on the constituents of Chloranthus japonicus sieb.
We have been studying secondary metabolites of plants growing in Hokkaido, Japan, in order to search for new natural templates of therapeutic agents. As part of this research program, we have investigated for constituents of plants belonging to the genus Chloranthus (Chloranthaceae). This genus contains about 10 species, which distributed in the tropical zone of Asia and in the temperate zone of East Asia. Several lindenane-sesquiterpene dimers with complex structures and unique biological activities have been isolated from Chloranthus plants.
The extract of Chloranthus japonicus was separated by repeated column chromatography to give three new compounds. Their structures were determined by analyses of the spectroscopic data. The isolation and structure elucidation of these compounds will be presented.