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DOI: 10.1055/s-0029-1246724
Sorin Freedom Solo® vs. Edwards Mitroflow®: a one year follow up
Objectives: In 2005, a new pericardial stentless prosthesis for supraanular aortic valve replacement, the Sorin Freedom Solo© was introduced. The new design totally made of bovine pericard potentially increases the implantable valve size.
Methods: In this prospective non-randomized observational study two patient groups receiving either the Freedom Solo® (group I, „I“) or Mitroflow® (group II, „II“) were monitored by transthoracic echocardiography (TTE). Measured parameters were pre-operative and 1 year post-operative orifice area (OA), peak (Δppeak) and mean (Δpmean) transvalvular pressure gradients, left ventricular endsystolic (LVESD) and enddiastolic (LVEDD) diameters, intraventricular septum thickness (IVST) and posterior wall enddiastolic thickness (PWEDT).
Results: Between 2007 and 2008, 82 pts (I: 55, II: 27) were included. Demographic data, in particular hemodynamic data were similar. 59 needed a single valve procedure (I: 45, II: 14), 23 pts needed concomitant cardiac surgery (I: 10, II: 13). The orifice area increased from 0.8 to 1.6cm2 in group I and from 0.7 to 1.0 in group II. Mean pressure gradients were reduced significantly (I: 52 to 9mmHg, II: 49 to 16mmHg).
During 1 year LVEDD showed a change from 46 to 40mm in group I and from 44 to 47 in group II as a sign for left ventricular remodeling. No paravalvular leakage was detected.
Conclusion: The new Freedom Solo® shows improved hemodynamic parameters and better LV re-remodeling during 1 year post-OP compared to the Mitroflow®. Implantation is technically simple and safe. Long term follow up has to confirm these early encouraging results.