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Klin Monbl Augenheilkd 2010; 227(4): 342-344
DOI: 10.1055/s-0029-1245251
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© Georg Thieme Verlag KG Stuttgart · New York

Fluorescein and Indocyanine Green Angiography Findings in B Cell Lymphoblastic Leukemia Mimicking Acute Central Serous Chorioretinopathy

Fluoreszein- und Indozyaningrün-Angiografiebefunde bei B Cell lymphoblastischer Leukämie die sich wie akut zentrale seröse Chorioretinopathie präsentiertA. P. Moulin, M. Bucher, J. A. Pournaras, C. Nguyen, A. Ambresin
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Publication Date:
20 April 2010 (online)

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Acute central serous chorioretinopathy (CSC) is a common idiopathic disorder with serous neurosensory and retinal pigment epithelium detachment of the posterior pole typically affecting male patients between 20 and 50 years old and is usually self limited. The fluorescein angiographic (FA) typically shows early dotlike hyperfluorescence with progressive leakage by the end of the arterial phase in a smokestack or inkblot-like manner. Indocyanine green (ICG) angiography confirms leakage points seen in the FA and allows better assessment of the exact extent of the choroidal exudation.

The differential diagnosis of acute CSC appears crucial as it may reveal a masquerade syndrome with underlying potentially ominous disease.

We hereby present a case of choroidal leukemic infiltration mimicking acute CSC and, to our knowledge, the first description of the ICG angiography features.

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Alexandre P. Moulin, MD

Jules Gonin Eye Hospital

Av. de France 15

1004 Lausanne, Switzerland

Phone: ++ 41/21/6 26 85 41

Fax: ++ 41/21/6 26 83 25

Email: alexandre.moulin@fa2.ch

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