Download PDF
Klin Monbl Augenheilkd
DOI: 10.1055/a-2114-4953
Der interessante Fall

Lamellar Macular Hole-Associated Epiretinal Proliferation with Cystoid Changes: Long-term Follow-up

Zystoide Veränderungen eines lamellären Makulalochs mit epiretinaler Proliferation im Langzeitverlauf
Ayse Guzin Taslipinar Uzel 
1   Ophthalmology, Ufuk University, 06836 Ankara, Turkey
,
Jonas Neubauer 
2   Ophthalmology, Eberhard-Karls-University Tübingen, Medical Faculty, Tübingen, Germany
,
Faik Gelisken
2   Ophthalmology, Eberhard-Karls-University Tübingen, Medical Faculty, Tübingen, Germany
› Author Affiliations
› Further Information
Also available at
    Permissions and Reprints

Introduction

Lamellar macular hole (LMH) was described by Gass as an oval red lesion using slit lamp biomicroscopy [1]. Recently, the diagnostic criterion of the LMH is defined by spectral-domain optical coherence tomography (SD-OCT) [2]. Epiretinal proliferation (EP) is homogenous material that covers the surface of the retina and is seen frequently in eyes with an LMH [3]. Even though the natural course of LMH is relatively stable, a tendency of morphological progression characterized by an increase in LMH diameter, a decrease in foveal thickness, and disruption of the ellipsoid zone (EZ) is known [4], [5]. Our knowledge of the morphological changes in EP associated with LMH is limited [4], [5]. The EP area may increase with the progression of the LMH [5]. Cystoid changes within EP have been reported in cases accompanied by various retinal pathologies [4], [6], [7]. We present a case of an LMH associated with EP, without any other accompanying retinal disorder that developed cystoid changes within the EP during a long-term follow-up of 8 1/2 years.



Publication History

Received: 07 April 2023

Accepted: 03 June 2023

Accepted Manuscript online:
21 June 2023

Article published online:
29 August 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Gass JDM. Lamellar macular hole: a complication of cystoid macular edema after cataract extraction. Arch Ophthalmol 1976; 94: 793-800
    CrossrefPubMedGoogle Scholar
  • 2 Hubschman JP, Govetto A, Spaide RF. et al. Optical coherence tomography-based consensus definition for lamellar macular hole. Br J Ophthalmol 2020; 104: 1741-1747
    CrossrefPubMedGoogle Scholar
  • 3 Pang CE, Spaide RF, Freund KB. Epiretinal proliferation seen in association with lamellar macular holes: a distinct clinical entity. Retina 2014; 34: 1513-1523
    CrossrefPubMedGoogle Scholar
  • 4 Pang CE, Spaide RF, Freund KB. Comparing functional and morphologic characteristics of lamellar macular holes with and without lamellar hole-associated epiretinal proliferation. Retina 2015; 35: 720-726
    CrossrefPubMedGoogle Scholar
  • 5 Compera D, Schumann RG, Cereda MG. et al. Progression of lamellar hole-associated epiretinal proliferation and retinal changes during long-term follow-up. Br J Ophthalmol 2018; 102: 84-90
    CrossrefPubMedGoogle Scholar
  • 6 Mandviwala MM, Weinberg DV, Hwang ES. Edema within Epiretinal Proliferation in a Diabetic Patient. Ophthalmology 2019; 126: 1272
    CrossrefPubMedGoogle Scholar
  • 7 Siedlecki J, Vounotrypidis E, Vogt D. et al. Lamellar hole-associated epiretinal proliferation presenting with perifoveal exudative vascular anomalous complex. Am J Ophthalmol Case Rep 2019; 14: 112-116
    CrossrefPubMedGoogle Scholar
  • 8 Compera D, Entchev E, Haritoglou C. et al. Lamellar Hole-Associated Epiretinal Proliferation in Comparison to Epiretinal Membranes of Macular Pseudoholes. Am J Ophthalmol 2015; 160: 373-384
    CrossrefPubMedGoogle Scholar
  • 9 Pang CE, Maberley DA, Freund KB. et al. Lamellar hole-associated epiretinal proliferation. Retina 2016; 36: 1408-1412
    CrossrefPubMedGoogle Scholar
  • 10 Querques G, Coscas F, Forte R. et al. Cystoid macular degeneration in exudative age-related macular degeneration. Am J Ophthalmol 2011; 152: 100-107
    CrossrefPubMedGoogle Scholar