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CC BY-NC-ND 4.0 · Endosc Int Open 2021; 09(10): E1472-E1479
DOI: 10.1055/a-1518-6754
Original article

Clinical and endoscopic characteristics of post-colonoscopy colorectal cancers detected within 10 years after a previous negative examination[*]

Kenta Kodama‡
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
2   Division of Gastroenterology, Japanese Red Cross Society Fukushima Hospital, Fukushima, Japan
,
Shin-ei Kudo
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Hideyuki Miyachi‡
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Kunihiko Wakamura
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yasuharu Maeda
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Katsuro Ichimasa
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yushi Ogawa
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yuta Kouyama
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Masahiro Abe
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yohei Ogura
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Taishi Okumura
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Kenichi Mochizuki
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yosuke Minegishi
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Misaki Ishiyama
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Yuichi Mori
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Masashi Misawa
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Toyoki Kudo
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Takemasa Hayashi
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Fumio Ishida
1   Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
,
Daisuke Watanabe
3   Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
4   Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States
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Abstract

Background and study aims We sometimes encounter colorectal cancer (CRC) that is discovered during the time interval between initial colonoscopy and the recommended follow-up examination. Although several studies reported such cases of CRC, most were based on registry data, which implied that the endoscopic quality was not consistent or guaranteed. We aimed to clarify these clinical and endoscopic characteristics at our high-volume center where a retrospective survey could be precisely performed.

Patients and methods We retrospectively analyzed patients with CRC who underwent endoscopic resection or surgery from April 2002 to December 2010, categorizing them into two groups: a “study group” of patients with a negative colonoscopy during the previous 10 years, and a “control group” of patients without a previous colonoscopy or with a previous colonoscopy more than 10 years prior.

Results A total of 2042 patients had CRC, among which 55 patients were classified into the study group and the remaining 1989 into the control group. The CRC cases in the study group showed a significant association with smaller (< 30 mm) tumor size (odds ratio [OR] 2.3; 95 % confidence interval [CI] 1.3–4.0) and proximal tumor site (OR 1.7; 95 %CI 0.9–2.9). In addition, right-sided and depressed-type T1 CRCs were significantly more common in the study group.

Conclusions Tumor size and location were associated with CRCs detected within 10 years after the negative examination. In addition, depressed-type T1 CRCs were more common. Therefore, we should pay more attention to small, right-sided, or depressed-type tumors in daily colonoscopy.

* Meeting presentations: Part of the present study was presented at the United European Gastroenterology Week 2013, Berlin, Germany, 16th October 2013 (poster presentation).




Publication History

Received: 29 June 2020

Accepted: 01 February 2021

Article published online:
16 September 2021

© 2021. The Author (s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

Comment to this article:

Endoscopy International Open – recently publishedEndoscopy 2021; 53(11): 1193-1193
DOI: 10.1055/a-1543-3445

 

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