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Zeitschrift für Phytotherapie 2020; 41(05): 251-255
DOI: 10.1055/a-1200-5230
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Liguster – eine (un)bekannte vergessene Arzneipflanze?

Matthias F Melzig
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Zusammenfassung

Der Liguster, Ligustrum vulgare L., gehört zu den vergessenen Arzneipflanzen, dessen Blätter, historisch belegt, v. a. zur Entzündungshemmung im Mund- und Halsbereich genutzt wurden. Der Nachweis relevanter Mengen an Secoiridoiden, wie Oleuropein, sowie Flavonoiden und Phenylpropanoiden stützen diese Indikation und sollten neue pharmakologische Untersuchungen an Ligusterblättern rechtfertigen.

Abstract

Privet: A seemingly forgotten herbal remedy

Ligustrum vulgare L. (wild privet) seems to be a forgotten medicinal plant. Its leaves were traditionally used to cure minor inflammations in the mouth or the throat. The presence of secoiridoids, like oleuropein, flavonoids and phenylpropanoids in the leaves support these ethnomedical indications and might justify further pharmacological investigations.

Schlüsselwörter

Ligustrum vulgare L. - Liguster - Oleaceae - traditionelle Medizin - Pharmakologie

Key words

Ligustrum vulgare L. - privet - Oleaceae - traditional medicine - pharmacology


Publication History

Article published online:
19 October 2020

© 2020. Thieme. All rights reserved.

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  • Literatur

  • 1 Hegi G. Ligustrum . In: Hegi G. Illustrierte Flora von Mitteleuropa. Bd. V, Teil 3. Berlin, Hamburg: Verlag Paul Parey; 1975: 1944-1949
    Google Scholar
  • 2 Fuchs L. Von Beinhöltzlin. In: Fuchs L. New Kreüterbuch. Basel 1543. Köln: Taschen-Verlag; 2001. Cap. CLXXXII
    Google Scholar
  • 3 Bock H. Beinhültzen. In: Bock H. Teutsche Speißkammer. Straßburg: Wendel Rihel; 1550: 787-789
    Google Scholar
  • 4 Pieroni A, Pachaly P. An ethnopharmacological study on common privet (Ligustrum vulgare) and phillyrea (Phillyrea latifolia). Fitoterapia 2000; 71 (Suppl. 1): S89-S94
    CrossrefPubMedGoogle Scholar
  • 5 Möller L, Vogel M. Hrsg. Die Naturgeschichte des Caius Plinius Secundus Bd. 3. Wiesbaden: marixverlag; 2007: 638
    Google Scholar
  • 6 Möller L, Vogel M. Hrsg. Die Naturgeschichte des Caius Plinius Secundus Bd. 4.. Wiesbaden: marixverlag; 2007: 154
    Google Scholar
  • 7 Stückrath K. Bibelgärten. Göttingen: Vandenhoeck & Ruprecht; 2012: 349
    CrossrefGoogle Scholar
  • 8 Wynn SG, Fougere B. Veterinary Herbal Medicine. St. Louis, Miss., USA: Mosby Elsevier; 2007: 386
    Google Scholar
  • 9 Czerwinska ME, Ziarek M, Bazylko A. et al. Quantitative determination of secoiridoids and phenylpropanoids in different extracts of Ligustrum vulgare L. leaves by a validated HPTLC – photodensitometry method. Phytochem Anal 2015; 26: 253-260
    CrossrefPubMedGoogle Scholar
  • 10 Gießel JM, Zaar A, Schäfer R. et al. Facile access to oleuropein and hydroxytyrosol from Ligustrum vulgare—A plant material growing all over Eurasia. Mediterr J Chem 2018; 7: 217-222
    CrossrefPubMedGoogle Scholar
  • 11 Czerwińska ME, Duszak K, Parzonko A, Kiss AK. Chemical composition and UVA-protecting activity of extracts from Ligustrum vulgare and Olea europaea leaves. Acta Biol Cracov Bot 2016; 58 (2): 45-55
    PubMedGoogle Scholar
  • 12 Mucaji P, Zahradnikova A, Bezakova L. et al. HPLC Determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents. Molecules 2011; 16: 8198-8208
    CrossrefPubMedGoogle Scholar
  • 13 Woźniak M, Michalak B, Wyszomierska J. et al. Effects of phytochemically characterized extracts from Syringa vulgaris and isolated secoiridoids on mediators of inflammation in a human neutrophil model. Front Pharmacol 2018; 9: 349
    CrossrefPubMedGoogle Scholar
  • 14 Cazander G, Jukema GN, Nibbering PH. Complement activation and inhibition in wound healing. Clin Dev Immunol 2012; 2012: 534291
    CrossrefPubMedGoogle Scholar
  • 15 Castejón ML, Montoya T, Alarcón-de-la-Lastra C. et al. Potential protective role exerted by secoiridoids from Olea europaea L. in cancer, cardiovascular, neurodegenerative, aging-related, and immunoinflammatory diseases. Antioxidants (Basel) 2020; 9: 149
    CrossrefPubMedGoogle Scholar
  • 16 Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm 2010; 78: 133-154
    CrossrefPubMedGoogle Scholar
  • 17 Nekooeian AA, Khalili A, Khosravi MB. Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension. Indian J Pharmacol 2014; 46: 398-403
    CrossrefPubMedGoogle Scholar
  • 18 Kiss AK, Mańk M, Melzig MF. Dual inhibition of metallopeptidases ACE and NEP by extracts, and iridoids from Ligustrum vulgare L. J Ethnopharmacol 2008; 120: 220-225
    CrossrefPubMedGoogle Scholar
  • 19 Saibandith B, Spencer JPE, Rowland IR, Commane DM. Olive polyphenols and the metabolic syndrome. Molecules 2017; 22: 1082
    CrossrefPubMedGoogle Scholar
  • 20 He F, Chen L, Liu Q, Wang X. et al. Preparative separation of phenylethanoids and secoiridoid glycosides from Ligustri lucidi fructus by high-speed counter-current chromatography coupled with ultrahigh pressure extraction. Molecules 2018; 23: 3353
    CrossrefPubMedGoogle Scholar
  • 21 Bundesanzeiger vom 06.05.2000, Jahrgang 52, Nr. 86, S. 8517
    PubMed
  • 22 Wagstaff DJ. International Poisonous Plants Checklist. Boca Raton Fl USA: CRC Press; 2008: 235
    CrossrefGoogle Scholar
  • 23 Teuscher E, Lindequist U. Biogene Gifte. 3.. Aufl. Stuttgart: WVG; 2010: 696
    Google Scholar