Alkaloids from Aspidosperma Species from Bolivia

A.-C. Mitaine; K. Mesbah; B. Richard; C. Petermann; S. Arrazola; C. Moretti; M. Zèches-Hanrot; L. Le Men-Olivier

doi:10.1055/s-2006-957939

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Planta Med 1996; 62(5): 458-461
DOI: 10.1055/s-2006-957939

Paper

Alkaloids from Aspidosperma Species from Bolivia

A.-C. Mitaine¹ , K. Mesbah¹ , B. Richard¹ , C. Petermann¹ , S. Arrazola² , C. Moretti³ , M. Zèches-Hanrot¹ , L. Le Men-Olivier¹

¹Faculté de Pharmacie (U.R.A. au C.N.R. S. n° 492), 51, rue Cognacq-Jay, F-51096 Reims Cedex, France
²C.I.B.E. Universidad Mayor de San Simon, C. P. 992 Cochabamba, Bolivia
³ORSTOM (UR n° 45), 213 me Lafayette, F-75480 Paris Cedex 10, France

Further Information

Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

Two Bolivian Aspidosperma species were investigated. The seed and stem bark of Aspidosperma macrocarpon Mart. contain six known alkaloids: (-)-vincadifformine, ervinceine, kopsanone, kopsinine, kopsanol in the seed, and kopsanone, kop-sinine, kopsanol, 18-epikopsanol in the stem bark. The stem bark of Aspidosperma pyrifolium Mart. contains eleven known alkaloids: (-)-vincadifformine, O-demethylpalosine, haplocine, N-formylaspidospermidine, vallesine, demethoxyaspidospermine, palosine, (-)-aspidospermine, aspidospermidine, akuammicine, tubotaiwine, beside the two new bases dehydroxyhaplocidine and 10-methoxyaspidospermidine.

Key words

Aspidosperma macrocarpon - A. pyrifolium - Apocynaceae - indole alkaloids

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