Issue 5, 1973

Electrophilic substitution in indoles. Part VII. Cyclisation of 1- and 2-methylindolylbutanols and their toluene-p-sulphonates

Abstract

4-(1-Methylindol-3-yl)butan-1-ol cyclises to 9-methyltetrahydrocarbazole on heating with boron trifluoride–ether and the same product is also formed from alkaline or neutral solvolyses of the corresponding tosylate. The analogous 2-methylindolylbutanol and its tosylate under the same conditions affords a spirocyclic 3H-indole.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 2, 1973, 548-551

Electrophilic substitution in indoles. Part VII. Cyclisation of 1- and 2-methylindolylbutanols and their toluene-p-sulphonates

A. H. Jackson and B. Naidoo, J. Chem. Soc., Perkin Trans. 2, 1973, 548 DOI: 10.1039/P29730000548

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