Issue 17, 1996
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Nucleophilic substitution of protected β-bromoethyl cyclohexadiene-cis-diol as an alternative to direct microbial oxidation of β-functionalized phenethyl substrates

Tomas Hudlicky,   Mary Ann A. Endoma  and  Gabor Butora  

Abstract

(5S,6R)-1-(2-Bromoethyl)-5,6-(propane-2,2-diyldioxy)cyclohexa-1,3-diene 6 is subjected to nucleophilic substitution reaction using C-, N-, O- and S-based nucleophiles. The yields of the products are compared with those obtained by direct microbial oxidation of the corresponding aromatic substrates. The enantiomeric excess and isolated yield for each compound are reported.

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Article information

DOI
https://doi.org/10.1039/P19960002187
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1996, 2187-2192

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Nucleophilic substitution of protected β-bromoethyl cyclohexadiene-cis-diol as an alternative to direct microbial oxidation of β-functionalized phenethyl substrates

T. Hudlicky, M. A. A. Endoma and G. Butora, J. Chem. Soc., Perkin Trans. 1, 1996, 2187 DOI: 10.1039/P19960002187

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