Issue 1, 1988
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Chemistry of 2-bromo-2-methylpropanamides. Synthesis and solvolytic behaviour of oxazolidinones and spiro-oxazolidinones

Paolo Scrimin,   Giorgio Cavicchioni,   Ferruccio D'Angeli,   Amiram Goldblum  and  Flavio Maran  

Abstract

The base-promoted reaction of 2-bromo-2-methylpropanamides (1) with 5-, 6-, and 7-membered lactams (2) affords spiro-oxazolidinones (3). The latter compounds are hydrolysed under acidic conditions to yield the ω-aminoester amides (7). The solvolytic behaviour of some monocyclic oxazolidinones obtained upon reaction of common amides with 2-bromoamides (1) is also reported.

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Article information

DOI
https://doi.org/10.1039/P19880000043
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1988, 43-47

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Chemistry of 2-bromo-2-methylpropanamides. Synthesis and solvolytic behaviour of oxazolidinones and spiro-oxazolidinones

P. Scrimin, G. Cavicchioni, F. D'Angeli, A. Goldblum and F. Maran, J. Chem. Soc., Perkin Trans. 1, 1988, 43 DOI: 10.1039/P19880000043

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