A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

Fatemeh Ganjali; Mostafa Ghafori Gorab; Hooman Aghamirza Moghim Aliabadi; Saman Rahmati; Reza Ahangari Cohan; Reza Eivazzadeh-Keihan; Ali Maleki; Hossein Ghafuri; Mohammad Mahdavi

doi:10.1039/D3RA02822D

A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

Fatemeh Ganjali,^a Mostafa Ghafori Gorab,^a Hooman Aghamirza Moghim Aliabadi,

^b Saman Rahmati,^c Reza Ahangari Cohan,^d Reza Eivazzadeh-Keihan,*^d Ali Maleki,

*^a Hossein Ghafuri

^a and Mohammad Mahdavi

*^e

Author affiliations

* Corresponding authors

^a Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
E-mail: maleki@iust.ac.ir
Fax: +98-21-73021584
Tel: +98-21-73228313

^b Advanced Chemical Studies Lab, Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran

^c Protein Chemistry Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran

^d Nanobiotechnology Department, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran
E-mail: reza.tab_chemist@yahoo.com

^e Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
E-mail: momahdavi@sina.tums.ac.ir

Abstract

A novel and biologically active nanobiocomposite is synthesized based on carbon nitride nanosheet (g-C₃N₄) based carboxymethylcellulose hydrogels with embedded zinc ferrite nanoparticles. Physical-chemical aspects, morphological properties, and their multifunctional biological properties have been considered in the process of evaluation of the synthesized structure. The hydrogels' compressive strength and compressive modulus are 1.98 ± 0.03 MPa and 3.46 ± 0.05 MPa, respectively. Regarding the biological response, it is shown that the nanobiocomposite is non-toxic and biocompatible, and hemocompatible (with Hu02 cells). In addition, the developed material offers a suitable antibacterial activity for both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli).

Article information

https://doi.org/10.1039/D3RA02822D

Article type

Paper

Submitted

28 Apr 2023

Accepted

08 Jul 2023

First published

19 Jul 2023

This article is Open Access

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RSC Adv., 2023,13, 21873-21881

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A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

F. Ganjali, M. G. Gorab, H. A. Moghim Aliabadi, S. Rahmati, R. A. Cohan, R. Eivazzadeh-Keihan, A. Maleki, H. Ghafuri and M. Mahdavi, RSC Adv., 2023, 13, 21873 DOI: 10.1039/D3RA02822D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

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A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

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