A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Qing-yu Ma; Xiang Li; Wei Zhou; Xia-fen Li; Yi-chen Liu; Gai-li Feng; Hongwei Tan; Yuan Zhang; Guo-wen Xing

doi:10.1039/D3CC02788K

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential†

Qing-yu Ma,‡^a Xiang Li,‡^a Wei Zhou,^a Xia-fen Li,^a Yi-chen Liu,^a Gai-li Feng,^a Hongwei Tan,

^a Yuan Zhang*^ab and Guo-wen Xing

*^a

Author affiliations

* Corresponding authors

^a College of Chemistry, Beijing Normal University, Beijing, China
E-mail: yuanzhang@bnu.edu.cn, gwxing@bnu.edu.cn

^b Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China

Abstract

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.

Download options Please wait...

Supplementary files

Supplementary information PDF (3297K)

Article information

DOI: https://doi.org/10.1039/D3CC02788K
Article type: Communication
Submitted: 09 Jun 2023
Accepted: 24 Jul 2023
First published: 24 Jul 2023

Download Citation

Chem. Commun., 2023,59, 10287-10290

Permissions

Request permissions

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Q. Ma, X. Li, W. Zhou, X. Li, Y. Liu, G. Feng, H. Tan, Y. Zhang and G. Xing, Chem. Commun., 2023, 59, 10287 DOI: 10.1039/D3CC02788K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential†

Abstract

Supplementary files

Article information

Download Citation

Permissions

A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential

Social activity

Search articles by author

Spotlight

Advertisements