Issue 19, 2019

Synthesis of pyrazolylvinyl ketones from furan derivatives

Abstract

A new protocol for the synthesis of pyrazol-5-ylvinyl ketones, e.g. pyrazole-chalcones, employing furfuryl ketones as a triketone equivalent, has been developed. The reaction occurs under mild conditions and does not require the use of expensive materials. Other important benefits include the simplicity and atom efficiency of this approach.

Graphical abstract: Synthesis of pyrazolylvinyl ketones from furan derivatives

Supplementary files

Article information

Article type
Paper
Submitted
26 Mar 2019
Accepted
17 Apr 2019
First published
18 Apr 2019

Org. Biomol. Chem., 2019,17, 4850-4855

Synthesis of pyrazolylvinyl ketones from furan derivatives

N. Sawengngen, P. N. Chalikidi, S. Araby, F. Hampel, P. Gmeiner and O. V. Serdyuk, Org. Biomol. Chem., 2019, 17, 4850 DOI: 10.1039/C9OB00701F

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