Issue 82, 2019

A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media

Abstract

We present an NMR method based on natural abundance 17O relaxation of water to determine effective viscosity in biological aqueous samples. The method accurately captures viscosity of dilute and crowded protein solutions and offers a fairly simple way to quantify the internal fluidity of biological condensates formed through phase separation.

Graphical abstract: A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media

Supplementary files

Article information

Article type
Communication
Submitted
07 Aug 2019
Accepted
23 Sep 2019
First published
23 Sep 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2019,55, 12404-12407

A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media

N. Rezaei-Ghaleh, F. Munari, S. Becker, M. Assfalg and C. Griesinger, Chem. Commun., 2019, 55, 12404 DOI: 10.1039/C9CC06124J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements