Issue 12, 2019
From the journal:

Chemical Communications

Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing†

Yongchao Song,a   Tailin Xu, ORCID logo *a   Li-Ping Xu*a  and  Xueji Zhang*a  

* Corresponding authors

a Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China
E-mail: xutailin@ustb.edu.cn, xuliping@ustb.edu.cn, zhangxueji@ustb.edu.cn

Abstract

A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.

Graphical abstract: Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing

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Article information

DOI
https://doi.org/10.1039/C8CC09586H
Article type
Communication
Submitted
02 Dec 2018
Accepted
09 Jan 2019
First published
10 Jan 2019

Chem. Commun., 2019,55, 1742-1745

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Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing

Y. Song, T. Xu, L. Xu and X. Zhang, Chem. Commun., 2019, 55, 1742 DOI: 10.1039/C8CC09586H

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