Issue 13, 2017

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

Abstract

Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small peptidomimetic nanospheres.

Graphical abstract: Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

Supplementary files

Article information

Article type
Communication
Submitted
14 Dec 2016
Accepted
25 Jan 2017
First published
25 Jan 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 2178-2181

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

K. H. A. Lau, V. Castelletto, T. Kendall, J. Sefcik, I. W. Hamley, M. Reza and J. Ruokolainen, Chem. Commun., 2017, 53, 2178 DOI: 10.1039/C6CC09888F

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