Issue 44, 2014
From the journal:

Journal of Materials Chemistry B

Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency†

Jun Zhang,a   Anthony P. Raphael,b   Yannan Yang,a   Amirali Popat,cd   Tarl W. Prowb  and  Chengzhong Yu*a  

* Corresponding authors

a Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia
E-mail: c.yu@uq.edu.au

b Dermatology Research Centre, School of Medicine, The University of Queensland, Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD 4102, Australia

c The School of Pharmacy, The University of Queensland, Brisbane, QLD 4072, Australia

d Mucosal Diseases Group, Mater Research Institute – The University of Queensland, Translational Research Institute, 37 Kent St, Woolloongabba, QLD 4102, Australia

Abstract

Using a pig ear skin model, it is demonstrated that silica vesicles show higher skin safety compared to dense silica nanoparticles with similar sizes. A hydrophobic UV blocker is efficiently dispersed in silica vesicles in an amorphous state, leading to ultrahigh UV-attenuating efficiency and a sun protection factor of 100 in a sunscreen formulation.

Graphical abstract: Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency

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Article information

DOI
https://doi.org/10.1039/C4TB01332H
Article type
Communication
Submitted
11 Aug 2014
Accepted
08 Sep 2014
First published
08 Sep 2014

J. Mater. Chem. B, 2014,2, 7673-7678

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Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency

J. Zhang, A. P. Raphael, Y. Yang, A. Popat, T. W. Prow and C. Yu, J. Mater. Chem. B, 2014, 2, 7673 DOI: 10.1039/C4TB01332H

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