Issue 43, 2013

Gold-catalyzed intermolecular reaction of 2-(1-alkynyl)-2-alken-1-ones with diarylethenes to construct polysubstituted cyclopenta[c]furans through a cascade heterocyclization/[3+2] cycloaddition sequence

Abstract

A method for preparing polysubstituted cyclopenta[c]furans from 2-(1-alkynyl)-2-alken-1-ones and diarylethenes via gold catalysis is reported. The reaction shows good regioselectivity to afford the desired product in moderate to excellent yields.

Graphical abstract: Gold-catalyzed intermolecular reaction of 2-(1-alkynyl)-2-alken-1-ones with diarylethenes to construct polysubstituted cyclopenta[c]furans through a cascade heterocyclization/[3+2] cycloaddition sequence

Supplementary files

Article information

Article type
Communication
Submitted
19 Aug 2013
Accepted
05 Sep 2013
First published
05 Sep 2013

RSC Adv., 2013,3, 19913-19916

Gold-catalyzed intermolecular reaction of 2-(1-alkynyl)-2-alken-1-ones with diarylethenes to construct polysubstituted cyclopenta[c]furans through a cascade heterocyclization/[3+2] cycloaddition sequence

T. He, P. Gao, Y. Qiu, X. Yan, X. Liu and Y. Liang, RSC Adv., 2013, 3, 19913 DOI: 10.1039/C3RA44467H

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