Issue 9, 2013
From the journal:

New Journal of Chemistry

Recognition of chiral carboxylates by 1,3-disubstituted thioureas with 1-arylethyl scaffolds†

Karla Elisa Trejo-Huizar,a   Ricardo Ortiz-Rico,a   María de los Angeles Peña-Gonzáleza  and  Marcos Hernández-Rodríguez*a  

* Corresponding authors

a Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Del. Coyoacán, México, D.F., México
E-mail: marcoshr@unam.mx
Tel: +52 55-5622-4402

Abstract

Chiral thioureas with 1-arylethyl and 1-arylethyl-2-2-2-trifluoroethyl (Ar = Ph, 1-Napht, 9-Anthr) scaffolds were used as hosts to recognize acetate and chiral mandelates. The higher binding obtained with the trifluoromethyl analogue is also reflected in the higher selectivity factor for one enantiomer. The C2 symmetry was also indispensable to obtain selectivity.

Graphical abstract: Recognition of chiral carboxylates by 1,3-disubstituted thioureas with 1-arylethyl scaffolds

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3NJ00644A
Article type
Letter
Submitted
15 Jun 2013
Accepted
19 Jun 2013
First published
24 Jun 2013

New J. Chem., 2013,37, 2610-2613

Permissions

Request permissions

Recognition of chiral carboxylates by 1,3-disubstituted thioureas with 1-arylethyl scaffolds

K. E. Trejo-Huizar, R. Ortiz-Rico, M. D. L. A. Peña-González and M. Hernández-Rodríguez, New J. Chem., 2013, 37, 2610 DOI: 10.1039/C3NJ00644A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements