Issue 72, 2013

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Abstract

A new rhodamine fluorescent probe for monitoring ˙OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for ˙OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular ˙OH in live cells.

Graphical abstract: Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Supplementary files

Article information

Article type
Communication
Submitted
20 Jun 2013
Accepted
11 Jul 2013
First published
11 Jul 2013

Chem. Commun., 2013,49, 7959-7961

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

M. Kim, S. Ko, H. Kim, I. Shin and J. Tae, Chem. Commun., 2013, 49, 7959 DOI: 10.1039/C3CC44627A

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