Issue 10, 2012

Weight reduction effects of a black soy peptide supplement in overweight and obese subjects: Double blind, randomized, controlled study

Abstract

The present study determined the effect of black soy peptide supplementation on body weight and body fat in overweight/obese subjects. In a double-blind controlled trial, participants (n = 80) were randomized to either soy peptide supplementation (the test group) or to a placebo (the placebo group). Sixty-four people completed the study, and anthropometric parameters, serum inflammatory markers, and leptin and lipid profiles were measured. After 6 weeks, the test group (n = 35) had significant reductions in body weight (p = 0.003) and body mass index (BMI) (p = 0.004), body fat mass (p = 0.038). After 12 weeks, they also had significant reductions in body weight (p < 0.001), BMI (p < 0.001), body fat percentage (p = 0.002), and body fat mass (p = 0.001). However, these significances were not observed in the placebo group (n = 29). In addition, net changes in body weight and body fat mass in the test group were significantly bigger than those in the placebo group after 12 weeks. Leptin levels were significantly reduced in the test groups (p = 0.047), but were not observed in the placebo group (p = 0.323). Interestingly, the subjects with weight reductions ≥1kg in the test group had greater reductions in circulating leptin levels (p = 0.002). Additionally, fasting insulin levels were significantly reduced in the test groups. The conclusion is that black soy peptide supplementation may be beneficial for body weight control in overweight/obese subjects.

Graphical abstract: Weight reduction effects of a black soy peptide supplement in overweight and obese subjects: Double blind, randomized, controlled study

Supplementary files

Article information

Article type
Paper
Submitted
07 Nov 2011
Accepted
13 May 2012
First published
28 Jun 2012

Food Funct., 2012,3, 1019-1024

Weight reduction effects of a black soy peptide supplement in overweight and obese subjects: Double blind, randomized, controlled study

J. H. Kwak, C. Ahn, S. Park, S. Jung, B. Min, O. Y. Kim and J. H. Lee, Food Funct., 2012, 3, 1019 DOI: 10.1039/C2FO10244G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements