Issue 19, 2011

A kinetically controlled crystallization process for identifying new co-crystal forms: fast evaporation of solvent from solutions to dryness

Abstract

Fast evaporation of solvent from solutions to dryness by rotary evaporation is shown to be a useful technique for quick screening of APIs for possible new co-crystal forms. Faster crystallization kinetics of the process enhance the possibility of detecting metastable forms.

Graphical abstract: A kinetically controlled crystallization process for identifying new co-crystal forms: fast evaporation of solvent from solutions to dryness

Supplementary files

Article information

Article type
Communication
Submitted
17 Apr 2011
Accepted
24 Jun 2011
First published
22 Jul 2011

CrystEngComm, 2011,13, 5650-5652

A kinetically controlled crystallization process for identifying new co-crystal forms: fast evaporation of solvent from solutions to dryness

P. P. Bag, M. Patni and C. Malla Reddy, CrystEngComm, 2011, 13, 5650 DOI: 10.1039/C1CE05778B

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