Issue 5, 2010
From the journal:

Nanoscale

Development of Aunanoparticles dispersed carbon nanotube-based biosensor for the detection ofparaoxon

Neetu Jhaa  and  Sundara Ramaprabhu*a  

* Corresponding authors

a Alternative Energy and Nanotechnology Laboratory (AENL), Nano-Functional Materials Technology Centre (NFMTC), Department of Physics, Indian Institute of Technology Madras, Chennai 600 036, India
E-mail: ramp@iitm.ac.in
Fax: +91-44-22570509
Tel: +91-44-22574862

Abstract

A disposable and sensitive biosensor has been fabricated for the detection of the organophosphorous (OP) compound paraoxon using an amperometric technique. For the measurements, gold nanoparticles dispersed on the outer surface of multiwalled carbon nanotubes (Au-MWNTs) has been used as the electrode material, as it possesses high electron transfer rates and provides large immobilization sites for the bioenzymes, which combines with the high electrocatalytic activity of MWNTs for thiocholine oxidation at low potential. Au-MWNTs have been synthesized by chemically reducing Au salt over functionalized MWNTs, and the same has been characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and high resolution transmission electron microscopic (HRTEM) techniques. The ability of the Au-MWNTs nanocomposite-based biosensor has been demonstrated to reliably measure the concentration of paraoxon in the nanomolar range.

Graphical abstract: Development of Au nanoparticles dispersed carbon nanotube-based biosensor for the detection of paraoxon

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Article information

DOI
https://doi.org/10.1039/B9NR00336C
Article type
Paper
Submitted
04 Nov 2009
Accepted
24 Jan 2010
First published
17 Mar 2010

Nanoscale, 2010,2, 806-810

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Development of Au nanoparticles dispersed carbon nanotube-based biosensor for the detection of paraoxon

N. Jha and S. Ramaprabhu, Nanoscale, 2010, 2, 806 DOI: 10.1039/B9NR00336C

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