Issue 17, 2007

Increased single nucleotide discrimination in arrayed primer elongation by 4′C-modified primer probes

Abstract

Herein we describe the beneficial impact of immobilized 4′C-modified primer probes on detecting single nucleotide variations in arrayed primer extension by a DNA polymerase.

Graphical abstract: Increased single nucleotide discrimination in arrayed primer elongation by 4′C-modified primer probes

Supplementary files

Article information

Article type
Communication
Submitted
06 Nov 2006
Accepted
18 Dec 2006
First published
02 Jan 2007

Chem. Commun., 2007, 1692-1694

Increased single nucleotide discrimination in arrayed primer elongation by 4′C-modified primer probes

J. Gaster, G. Rangam and A. Marx, Chem. Commun., 2007, 1692 DOI: 10.1039/B616129D

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