Issue 6, 2007
From the journal:

Chemical Communications

A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles†

Chris V. Galliford,a   James S. Martenson,a   Charlotte Sterna  and  Karl A. Scheidt*a  

* Corresponding authors

a Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, USA
E-mail: scheidt@northwestern.edu
Fax: +1 847 491 7713
Tel: +1 847 491 6659

Abstract

Spiropyrrolidinyloxindole compounds are synthesized in moderate to excellent yield via a highly diastereoselective Cu(I)-catalysed three-component assembly reaction of an imine, diazo-compound and substituted olefin dipolarophile.

Graphical abstract: A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles

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Article information

DOI
https://doi.org/10.1039/B609155E
Article type
Communication
Submitted
28 Jun 2006
Accepted
18 Oct 2006
First published
06 Nov 2006

Chem. Commun., 2007, 631-633

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A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles

C. V. Galliford, J. S. Martenson, C. Stern and K. A. Scheidt, Chem. Commun., 2007, 631 DOI: 10.1039/B609155E

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