Volume 126, 2004
From the journal:

Faraday Discussions

Histological and microscopyFT-IR imaging study on the proliferative activity and angiogenesis in head and neck tumours

P. Bruni,a   C. Conti,a   E. Giorgini,a   M. Pisani,a   C. Rubinib  and  G. Tosi*a  

* Corresponding authors

a Dipartimento di Scienze dei Materiali e della Terra, Università Politecnica delle Marche, Ancona, Italy
E-mail: tosi@mta01.univpm.it

b Istituto di Anatomia Patologica, Università Politecnica delle Marche, Ancona, Italy

Abstract

Micro Fourier transform infrared spectroscopy enables one to study small samples because of the high quality spectra that can be obtained. Biochemical and morphological changes between control and pathological tissues of head and neck tumours have been monitored drawing three-dimensional chemical maps of the main vibrational modes in the regions of interest. Comparison between spectral and histological data shows a satisfactory degree of accordance. Among all, proliferating and regressive states of the tumours can be identified.

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Article information

DOI
https://doi.org/10.1039/B306787B
Article type
Paper
Submitted
13 Jun 2003
Accepted
17 Jul 2003
First published
09 Sep 2003

Faraday Discuss., 2004,126, 19-26

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Histological and microscopy FT-IR imaging study on the proliferative activity and angiogenesis in head and neck tumours

P. Bruni, C. Conti, E. Giorgini, M. Pisani, C. Rubini and G. Tosi, Faraday Discuss., 2004, 126, 19 DOI: 10.1039/B306787B

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