Issue 4, 2003
From the journal:

Dalton Transactions

All-iron hydrogenase: synthesis, structure and properties of {2Fe3S}-assemblies related to the di-iron sub-site of the H-cluster†

Mathieu Razavet,a   Sian C. Davies,a   David L. Hughes,a   J. Elaine Barclay,a   David J. Evans,a   Shirley A. Fairhurst,a   Xiaoming Liua  and  Christopher J. Pickett*a  

* Corresponding authors

a Biological Chemistry Department, John Innes Centre, Norwich, UK

Abstract

Tripodal dithiolate thioether ligands MeC(CH2SH)2CH2SR (R = Me or Ph) provide a route to {2Fe3S}-complexes and syntheses are described. X-Ray crystal structures for two {2Fe3S}-pentacarbonyl derivatives and that for the first carbonyl cyanide are reported, together with temperature dependent 1H-NMR, Mössbauer, FTIR and redox potential data. The NMR data establish fluctionality associated with inversion at the thioether sulfur in the carbonyl complexes. The Mössbauer data affirm that the coordination environment of the two iron atoms in a dicyanide bridging carbonyl intermediate are differentiated. Bridging carbonyl intermediates have been structurally and spectroscopically identified in resting and CO inhibited forms of the sub-site of all-iron hydrogenases; the observation of a thermally unstable {2Fe3S}-bridging carbonyl intermediate is discussed in this context.

Graphical abstract: All-iron hydrogenase: synthesis, structure and properties of {2Fe3S}-assemblies related to the di-iron sub-site of the H-cluster

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B209690K
Article type
Paper
Submitted
03 Oct 2002
Accepted
03 Dec 2002
First published
21 Jan 2003

Dalton Trans., 2003, 586-595

Permissions

Request permissions

All-iron hydrogenase: synthesis, structure and properties of {2Fe3S}-assemblies related to the di-iron sub-site of the H-cluster

M. Razavet, S. C. Davies, D. L. Hughes, J. E. Barclay, D. J. Evans, S. A. Fairhurst, X. Liu and C. J. Pickett, Dalton Trans., 2003, 586 DOI: 10.1039/B209690K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements