Issue 14, 2000
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Study of a tandem aldol–Tischtschenko reaction between chiral enolsilanes and aldehydes catalyzed by titanium(IV) isopropoxide

Christophe Delas,a   Olivier Blacquea  and  Claude Moïse*a  

* Corresponding authors

a Laboratoire de Synthèse et d’Electrosynthèse Organométalliques (UMR 5632), Faculté des Sciences, 6 bd Gabriel, Dijon, France

Abstract

The synthesis and structure determination of polypropionate is presented. An allyltitanium complex is first used in an allyltitanation reaction; titanium(IV) isopropoxide is next utilized as catalyst in an aldol–Tischtschenko reaction. This method promotes the formation of esters bearing five or six stereocenters in two steps with a very high level of diastereoselectivity and very high yield.

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B002008G
Article type
Paper
Submitted
13 Mar 2000
Accepted
23 May 2000
First published
27 Jun 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 2265-2270

Permissions

Request permissions

Study of a tandem aldol–Tischtschenko reaction between chiral enolsilanes and aldehydes catalyzed by titanium(IV) isopropoxide

C. Delas, O. Blacque and C. Moïse, J. Chem. Soc., Perkin Trans. 1, 2000, 2265 DOI: 10.1039/B002008G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements