Issue 1253, 1980
From the journal:

Analyst

Use of charge-transfer complexation in the spectrophotometric assay of antazoline and naphazoline in combination

Saied Belal,   M. Abdel-Hady Elsayed,   Mohamed E. Abdel-Hamid  and  Hassan Abdine  

Abstract

A simple and accurate spectrophotometric method is described for the assay of antazoline and naphazoline, combined in eye-nose drops in a ratio of 20 : 1. The major component, antazoline, is determined, without interference from naphazoline, by charge-transfer complexation with σ-acceptor iodine. After precipitation of antazoline with sodium carbonate, the minor component, naphazoline, can be determined using the π-acceptor chloranil. The accuracy of the method is assessed by the assay of a standard mixture of the two components containing the same proportions as the commercial preparation.

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Article information

DOI
https://doi.org/10.1039/AN9800500774
Article type
Paper

Analyst, 1980,105, 774-778

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Use of charge-transfer complexation in the spectrophotometric assay of antazoline and naphazoline in combination

S. Belal, M. A. Elsayed, M. E. Abdel-Hamid and H. Abdine, Analyst, 1980, 105, 774 DOI: 10.1039/AN9800500774

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