Issue 24, 2020

A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes

Abstract

We present a method for assessing the extracellular calcium concentration using 19F chemical shift imaging. Specifically, a custom made calcium-responsive and lanthanide-based 19F MRI probe that undergoes a strong and highly specific modulation of its signal upon coordination with calcium ions was developed and its performance is presented.

Graphical abstract: A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes

Supplementary files

Article information

Article type
Communication
Submitted
25 Dec 2019
Accepted
25 Feb 2020
First published
25 Feb 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 3492-3495

A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes

G. Gambino, T. Gambino, R. Pohmann and G. Angelovski, Chem. Commun., 2020, 56, 3492 DOI: 10.1039/C9CC09977H

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