Issue 3, 2019, Issue in Progress

Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center

Abstract

A Cu(II)/bisoxazoline ligand-promoted formal [4 + 1] cycloaddition of diazo esters with azoalkenes formed in situ has been developed. This strategy provides a potential protocol for the construction of dihydropyrazoles containing a quaternary center with good to excellent yields.

Graphical abstract: Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center

Supplementary files

Article information

Article type
Paper
Submitted
27 Oct 2018
Accepted
02 Jan 2019
First published
11 Jan 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 1487-1490

Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center

B. Chen, W. Chu and Q. Liu, RSC Adv., 2019, 9, 1487 DOI: 10.1039/C8RA08909D

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