Issue 34, 2018, Issue in Progress

Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance

Abstract

The development of mussel-inspired materials with enhanced mechanical and physiological characteristics is fascinating due to the resulting structural properties. In this work, based on a chemical reaction, 3-(3,4-dihydroxyphenyl)propionic acid and dopamine hydrochloride (DA), with a catechol group, were covalently grafted onto a bio-compatible polymer backbone of chitosan hydrochloride (CHI) and hyaluronic acid sodium (HA). A mussel-inspired water-resistant adhesive film that could adhere in water was then fabricated by an environmentally friendly layer-by-layer (LbL) process. The water-resistant adhesive film demonstrated a strong underwater mechanical connection (0.82 ± 0.19 MPa) and a high transmittance (more than 83%) in the visible region; these characteristics are beneficial for clinical observation. A free-standing water-resistant adhesive film with a high transmittance of over 83% was also demonstrated and obtained from a facial and effective mechanical exfoliation method. The free-standing film exhibited favorable adhesion capacity with porcine skin, making it attractive for applications in the biomedical field.

Graphical abstract: Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance

Supplementary files

Article information

Article type
Paper
Submitted
15 Apr 2018
Accepted
13 May 2018
First published
22 May 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 18904-18912

Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance

D. Wang, J. Zhang, Y. Zhong, M. Chu, W. Chang and Z. Yao, RSC Adv., 2018, 8, 18904 DOI: 10.1039/C8RA03214A

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