Issue 83, 2016
From the journal:

Chemical Communications

An efficient two-photon fluorescent probe for monitoring mitochondrial singlet oxygen in tissues during photodynamic therapy†

Hong-Wen Liu,‡a   Shuai Xu,‡a   Peng Wang,a   Xiao-Xiao Hu,a   Jing Zhang,a   Lin Yuan, ORCID logo a   Xiao-Bing Zhang*a  and  Weihong Tana  

* Corresponding authors

a Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
E-mail: xbzhang@hnu.edu.cn

Abstract

A promising two-photon fluorescent probe MNAH for detecting 1O2 during the PDT process in mitochondria was proposed for the first time. MNAH was successfully applied for two-photon imaging of 1O2 in living cells and tissues during the PDT process with deep-tissue imaging depth. MNAH can be a powerful molecular tool for studying 1O2 generation in mitochondria during the PDT process.

Graphical abstract: An efficient two-photon fluorescent probe for monitoring mitochondrial singlet oxygen in tissues during photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C6CC05880A
Article type
Communication
Submitted
17 Jul 2016
Accepted
16 Sep 2016
First published
21 Sep 2016

Chem. Commun., 2016,52, 12330-12333

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An efficient two-photon fluorescent probe for monitoring mitochondrial singlet oxygen in tissues during photodynamic therapy

H. Liu, S. Xu, P. Wang, X. Hu, J. Zhang, L. Yuan, X. Zhang and W. Tan, Chem. Commun., 2016, 52, 12330 DOI: 10.1039/C6CC05880A

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