Issue 52, 2015
From the journal:

Chemical Communications

Target protein induced cleavage of a specific peptide for prostate-specific antigen detection with positively charged gold nanoparticles as signal enhancer†

Ding Wang,a   Yingning Zheng,a   Yaqin Chai,a   Yali Yuan*a  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: y198688@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86-23-68253172
Tel: +86-023-68252277

Abstract

In this work, a new “signal-on” electrochemical biosensor for sensitive detection of prostate-specific antigen (PSA) was developed on the basis of target protein induced cleavage of a specific peptide with positively charged gold nanoparticles (AuNPs) as signal enhancer.

Graphical abstract: Target protein induced cleavage of a specific peptide for prostate-specific antigen detection with positively charged gold nanoparticles as signal enhancer

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Article information

DOI
https://doi.org/10.1039/C5CC02148K
Article type
Communication
Submitted
13 Mar 2015
Accepted
15 May 2015
First published
19 May 2015

Chem. Commun., 2015,51, 10521-10523

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Target protein induced cleavage of a specific peptide for prostate-specific antigen detection with positively charged gold nanoparticles as signal enhancer

D. Wang, Y. Zheng, Y. Chai, Y. Yuan and R. Yuan, Chem. Commun., 2015, 51, 10521 DOI: 10.1039/C5CC02148K

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