Issue 19, 2014

Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Abstract

An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.

Graphical abstract: Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Supplementary files

Article information

Article type
Communication
Submitted
20 Dec 2013
Accepted
16 Jan 2014
First published
16 Jan 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 2512-2514

Author version available

Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

R. W. Adams, L. Byrne, P. Király, M. Foroozandeh, L. Paudel, M. Nilsson, J. Clayden and G. A. Morris, Chem. Commun., 2014, 50, 2512 DOI: 10.1039/C3CC49659G

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