Issue 3, 2013
From the journal:

Biomaterials Science

Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond

Alexander Hoppe,a   Viviana Mouriñobc  and  Aldo R. Boccaccini*a  

* Corresponding authors

a Institute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany
E-mail: alexander.hoppe@ww.uni-erlangen.de, aldo.boccaccini@ww.uni-erlangen.de
Fax: +49 9131 85 28602
Tel: +49 9131 85 28600

b Faculty of Pharmacy and Biochemistry, UBA, Buenos Aires, Argentina
E-mail: vmourino@ffyb.uba.ar
Fax: +54 1149648271
Tel: +54 1149648271

c CONICET, Argentina

Abstract

Bioactive glasses (BG) are being widely used for bone tissue engineering applications due to their bioactivity (ability to form strong bonds to bone) and their stimulating effects on bone formation. Recently, progress has been made to enhance the biological impact of BGs by incorporating specific metallic ions in silicate (or phosphate) glasses, including boron, copper, cobalt, silver, zinc and strontium. This review summarizes the newest developments on novel compositions of bioactive glasses in the field of bone tissue engineering related to osteogenesis and angiogenesis. Furthermore, new applications areas for bioactive glasses, including nerve regeneration and cancer treatment, are highlighted.

Graphical abstract: Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond

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Article information

DOI
https://doi.org/10.1039/C2BM00116K
Article type
Minireview
Submitted
10 Aug 2012
Accepted
20 Oct 2012
First published
19 Nov 2012

Biomater. Sci., 2013,1, 254-256

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Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond

A. Hoppe, V. Mouriño and A. R. Boccaccini, Biomater. Sci., 2013, 1, 254 DOI: 10.1039/C2BM00116K

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