Issue 12, 2011

Decarboxylative biaryl synthesis in a continuous flow reactor

Abstract

A practical protocol was developed that allows performing decarboxylative cross-coupling reactions in continuous flow reactors. Various biaryls were thus synthesized from aromatic carboxylic acids and aryl triflates using a Cu/Pd-catalyst system.

Graphical abstract: Decarboxylative biaryl synthesis in a continuous flow reactor

Supplementary files

Article information

Article type
Communication
Submitted
21 Dec 2010
Accepted
13 Jan 2011
First published
07 Feb 2011

Chem. Commun., 2011,47, 3628-3630

Decarboxylative biaryl synthesis in a continuous flow reactor

P. P. Lange, L. J. Gooßen, P. Podmore, T. Underwood and N. Sciammetta, Chem. Commun., 2011, 47, 3628 DOI: 10.1039/C0CC05708H

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