Issue 6, 2008

Chemical site-selective prenylation of proteins§

Abstract

A direct thionation procedure allows conversion of allylic alcohols into the corresponding thiols, the products of which are immediately compatible with one-pot site-selective selenenyl sulfide mediated protein conjugation.

Graphical abstract: Chemical site-selective prenylation of proteins

Supplementary files

Article information

Article type
Paper
Submitted
07 Feb 2008
Accepted
25 Apr 2008
First published
02 May 2008

Mol. BioSyst., 2008,4, 558-561

Chemical site-selective prenylation of proteins

D. P. Gamblin, S. van Kasteren, G. J. L. Bernardes, J. M. Chalker, N. J. Oldham, A. J. Fairbanks and B. G. Davis, Mol. BioSyst., 2008, 4, 558 DOI: 10.1039/B802199F

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