Issue 1, 2004

Poly(dimethylsiloxane) hollow Abbe prism with microlenses for detection based on absorption and refractive index shift

Abstract

In this paper we report on an optical detection method that utilizes two physical effects for signal transduction, namely absorption and shift of refractive index. The device consists of a hollow prism and was fabricated by means of soft-lithography. It exhibits a high degree of monolithic integration. In order to keep down the amount of external equipment that is necessary to run the device, we were able to integrate several functions, such as focussing of light and alignment of optical fibres. Since all components are fabricated in the same material and in the same process, compatibility with other microfluidic devices or components can be achieved easily. The functional efficiency and the performance of the detector were tested by investigating solutions containing fluorescein, with concentrations between 5 and 1000 µM. The results clearly show the two regions in which the two physical effects are effective.

Article information

Article type
Paper
Submitted
05 Sep 2003
Accepted
14 Nov 2003
First published
05 Jan 2004

Lab Chip, 2004,4, 24-27

Poly(dimethylsiloxane) hollow Abbe prism with microlenses for detection based on absorption and refractive index shift

A. Llobera, R. Wilke and S. Büttgenbach, Lab Chip, 2004, 4, 24 DOI: 10.1039/B310836H

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