GDF15 is an anorectic hormone that signals organismal stress to the brain. New data suggest that GDF15 enhances tolerance to acute inflammation by modulating liver lipid metabolism and triglyceride availability in mice.
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Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19
European Journal of Medical Research Open Access 16 November 2023
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S.O.R. is an employee of the University of Cambridge and has provided remunerated consultancy services to the following pharmaceutical companies with an active or potential interest in GDF15: Pfizer, AstraZeneca, MedImmune and Novo-Nordisk. S.M.L. has no relevant conflicts of interest to declare.
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Lockhart, S.M., O’Rahilly, S. The wasting hormone GDF15 frees up fat to fight infection. Nat Metab 1, 935–936 (2019). https://doi.org/10.1038/s42255-019-0131-y
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DOI: https://doi.org/10.1038/s42255-019-0131-y
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Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19
European Journal of Medical Research (2023)