Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Blood disorders

Unmasking the elusive erythropoietin-producing ‘Norn’ cell

Nature Medicine volume 29, pages 1064–1065 (2023)Cite this article

Subjects

Single-cell analyses in humans and mice have revealed the identity of the erythropoietin producing cells of the kidney — opening up new avenues of research for anemia and related disorders.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: The identification of erythropoietin-producing ‘Norn’ cells.

References

  1. Jelkmann, W. Respir. Physiol. 63, 257–266 (1986).

    Article  CAS  PubMed  Google Scholar 

  2. Wojchowski, D. Nature 470, 40–40 (2011).

    Article  CAS  PubMed  Google Scholar 

  3. Kragesteen, A. G. et al. Nat. Med. https://doi.org/10.1038/s41591-023-02314-7 (2023).

    Article  PubMed  Google Scholar 

  4. Semenza, G. L. Annu. Rev. Med. 74, 307–319 (2023).

    Article  PubMed  Google Scholar 

  5. KDIGO. Kidney Int. Suppl. 2, 283–287 (2012).

  6. Abedini, A. et al. Preprint at bioRxiv https://doi.org/10.1101/2022.10.24.513598 (2022).

  7. Imeri, F. et al. Kidney Int. 95, 375–387 (2019).

    Article  CAS  PubMed  Google Scholar 

  8. Singh, A. K. et al. N. Engl. J. Med. 385, 2325–2335 (2021).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

    Amin Abedini, Konstantin A. Klötzer & Katalin Susztak

  2. Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

    Amin Abedini, Konstantin A. Klötzer & Katalin Susztak

  3. Penn/CHOP kidney Innovation Center, Philadelphia, PA, USA

    Amin Abedini, Konstantin A. Klötzer & Katalin Susztak

  4. Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

    Amin Abedini, Konstantin A. Klötzer & Katalin Susztak

  5. Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

    Konstantin A. Klötzer

Authors
  1. Amin Abedini
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Konstantin A. Klötzer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Katalin Susztak
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Katalin Susztak.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abedini, A., Klötzer, K.A. & Susztak, K. Unmasking the elusive erythropoietin-producing ‘Norn’ cell. Nat Med 29, 1064–1065 (2023). https://doi.org/10.1038/s41591-023-02322-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41591-023-02322-7

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing