In a genome-wide protein quantitative trait locus study, we identify the genetic determinants of the levels of 91 inflammation-related proteins in blood from over 15,000 people. By combining these data with studies on the genetics of immune-mediated diseases, we reveal how individual proteins contribute to specific disease risks.
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References
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This is a summary of: Zhao, J. H. et al. Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets. Nat. Immunol. https://doi.org/10.1038/s41590-023-01588-w (2023).
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Genomic map of inflammatory blood proteins. Nat Immunol 24, 1411–1412 (2023). https://doi.org/10.1038/s41590-023-01609-8
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DOI: https://doi.org/10.1038/s41590-023-01609-8
