Nature Reviews Genetics (2019) https://doi.org/10.1038/s41576-019-0114-6 Published online 27 March 2019
The authors regret to report a minor error in Figure 2C. The location of peaks in the variant allele frequency (VAF) distribution was incorrectly drawn and labelled. The correct labels are as follows. The illustrated tumour has 50% tumour cells, and non-tumour cells are assumed to be strictly diploid. Clonal mutations on 1 of 4 copies of tumour DNA (1 in 6 molecules) are at VAF=0.167 (tetraploid loci, green), clonal mutations in 1 of 3 copies of tumour DNA (1 in 5 molecules) are at VAF=0.2 (triploid loci, orange), and clonal mutations in 1 of 2 copies of tumour DNA (1 in 4 molecules) are at VAF=0.25 (diploid regions, blue). The neutral 1/f2-like tail is plotted in yellow. The lower detection threshold is drawn at VAF=0.03. The revised figure below is correctly labelled. We note that this figure is an illustration only.
Original and Corrected.
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Turajlic, S., Sottoriva, A., Graham, T. et al. Author Correction: Resolving genetic heterogeneity in cancer. Nat Rev Genet 21, 65 (2020). https://doi.org/10.1038/s41576-019-0188-1
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41576-019-0188-1
