Innovative solutions are needed to overcome the global disparity in patients awaiting kidney transplantation versus donor organs available. A new study reports a promising new strategy of transplanting kidneys from HCV-infected donors into HCV-uninfected recipients and treating their HCV with direct-acting antivirals post-transplant — recipients achieved HCV cure with excellent one-year kidney allograft function.
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N.A.T. has received institutional grant support from AbbVie, Allergan, BMS, Gilead and Merck. A.J.K. reports no competing interests.
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Kwong, A.J., Terrault, N.A. Use of hepatitis C viraemic organs in kidney transplantation: a need to hit the pause button?. Nat Rev Gastroenterol Hepatol 16, 5–6 (2019). https://doi.org/10.1038/s41575-018-0071-0
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DOI: https://doi.org/10.1038/s41575-018-0071-0