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BACTERIAL PATHOGENESIS

Staphylococcus aureus metabolites promote IL-10

Glycolytic Staphylococcus aureus generate lactate that targets specific histone deacetylases to stimulate the production of IL-10 and enable biofilm formation.

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Fig. 1: S. aureus use glycolysis to support proliferation as biofilms on prosthetic joints.

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Correspondence to Alice Prince.

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Prince, A. Staphylococcus aureus metabolites promote IL-10. Nat Microbiol 5, 1183–1184 (2020). https://doi.org/10.1038/s41564-020-00791-x

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