Bacteria encode many strategies to prevent or escape infection. Through the analysis of metagenomic dark matter, several novel defence systems were identified, some of which were engineered and characterized in vivo, showing that they provide resistance against viruses and plasmids.
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Barrangou, R., van der Oost, J. Mining for novel bacterial defence systems. Nat Microbiol 3, 535–536 (2018). https://doi.org/10.1038/s41564-018-0149-z
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DOI: https://doi.org/10.1038/s41564-018-0149-z
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