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CHROMATIN

The sight of transcription

Nature Cell Biology volume 24, pages 284–285 (2022)Cite this article

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What does an actively transcribing genomic locus look like? A recent study has taken advantage of large and highly expressed mammalian genes and used microscopy to find out. The discovery sheds light on transcription and its effect on chromosome structure and the spatial organization of gene loci.

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Fig. 1: Transcription loop structure.

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Authors and Affiliations

  1. MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK

    Elias T. Friman & Wendy A. Bickmore

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  1. Elias T. Friman
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  2. Wendy A. Bickmore
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Correspondence to Wendy A. Bickmore.

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The authors declare no competing interests

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Friman, E.T., Bickmore, W.A. The sight of transcription. Nat Cell Biol 24, 284–285 (2022). https://doi.org/10.1038/s41556-022-00865-4

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